Structure of PDB 8fky Chain SI

Receptor sequence
>8fkySI (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPLVPENLLKKRKAYQALKATQAKQALLARFKRLESFLHDSWRQKRDKV
RLRRLEVKPHALELPDKHSLAFVVRIERIDGVSLLVQRTIARLRLKKIFS
GVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNKTIPL
TDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHA
TKNRVGFLKEMGTPGYRGERINQLIRQLN
3D structure
PDB8fky Principles of human pre-60 S biogenesis.
ChainSI
Resolution2.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna SI R60 S63 R34 S37
BS02 rna SI L65 H66 W69 R70 K72 R73 V76 R79 R80 K84 P85 R104 D106 R230 L39 H40 W43 R44 K46 R47 V50 R53 R54 K58 P59 R78 D80 R204
BS03 rna SI I18 L20 Y32 K36 A223 R224 H225 I2 L4 Y16 K20 A197 R198 H199
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825 blastocyst formation
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8fky, PDBe:8fky, PDBj:8fky
PDBsum8fky
PubMed37410842
UniProtQ6DKI1|RL7L_HUMAN Ribosomal protein uL30-like (Gene Name=RPL7L1)

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