Structure of PDB 8fkv Chain SI

Receptor sequence
>8fkvSI (length=225) Species: 9606 (Homo sapiens) [Search protein sequence]
VPENLLKKRKAYQALKATQAKQALLARFKRLESFLHDSWRQKRDKVRLRR
LEVKPHALELPDKHSLAFVVRIERIDGVSLLVQRTIARLRLKKIFSGVFV
KVTPQNLKMLRIVEPYVTWGFPNLKSVRELILKRGQAKVKNKTIPLTDNT
VIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPFHLSVARHATKNR
VGFLKEMGTPGYRGERINQLIRQLN
3D structure
PDB8fkv Principles of human pre-60 S biogenesis.
ChainSI
Resolution2.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna SI R57 R60 R27 R30
BS02 rna SI H66 W69 K72 R73 V76 R80 K84 P85 H86 R104 D106 R230 H36 W39 K42 R43 V46 R50 K54 P55 H56 R74 D76 R200
BS03 rna SI K30 Y32 K36 R224 H225 K10 Y12 K16 R194 H195
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001825 blastocyst formation
Cellular Component
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8fkv, PDBe:8fkv, PDBj:8fkv
PDBsum8fkv
PubMed37410842
UniProtQ6DKI1|RL7L_HUMAN Ribosomal protein uL30-like (Gene Name=RPL7L1)

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