Structure of PDB 8rxx Chain SH

Receptor sequence
>8rxxSH (length=182) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence]
SSKTPKLFNKWSFEGLETSELALRDHISTTAAYVPHTSGRWQKRRFYKAR
MPIVERLANGLMFKGRGNGRKLQAARLLKHTLEIIHLLTDENPLQVVVDA
VSKGAPREDSTRRRQAVDVSPMRRVNEAIYQMCKGAREAAFRNLKSMPEC
LADEIVNASKGSSNSYAIKKKDEVERVAKANR
3D structure
PDB8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
ChainSH
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SH R41 Q43 R45 R46 K49 N60 L62 M63 F64 K65 R67 N69 G70 R71 K72 L73 Q74 R77 N134 Y138 F149 R150 L152 S154 M155 R40 Q42 R44 R45 K48 N59 L61 M62 F63 K64 R66 N68 G69 R70 K71 L72 Q73 R76 N126 Y130 F141 R142 L144 S146 M147
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxx, PDBe:8rxx, PDBj:8rxx
PDBsum8rxx
PubMed38722744
UniProtQ868B1

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