Structure of PDB 7mq8 Chain SG

Receptor sequence
>7mq8SG (length=389) Species: 9606 (Homo sapiens) [Search protein sequence]
ETAQEKKLRLAKLYLEQLRQQEEEKAEFEEDQVAGRLKEDVLEQRGRLQK
LVAKEIQAPASADIRVLRGHQLSITCLVVTPDDSAIFSAAKDCSIIKWSV
ESGRKLHVIPRAKKKPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQ
SCQHLYTFTGHRDAVSGLAFRRGTHQLYSTSHDRSVKVWNVAENSYVETL
FGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEESQLVFYGHQGSIDC
IHLINEEHMVSGADDGSVALWGLSKKRPLALQREAHGLRGEPGLEQPFWI
SSVAALLNTDLVATGSHSSCVRLWQCGEGFRQLDLLCDIPLVGFINSLKF
SSSGDFLVAGVGQEHRLGRWWRIKEARNSVCIIPLRRVP
3D structure
PDB7mq8 Nucleolar maturation of the human small subunit processome.
ChainSG
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SG R143 Q146 L147 R186 Q442 R448 R68 Q71 L72 R111 Q363 R369
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030515 snoRNA binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0006364 rRNA processing
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0031428 box C/D methylation guide snoRNP complex
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7mq8, PDBe:7mq8, PDBj:7mq8
PDBsum7mq8
PubMed34516797
UniProtO43818|U3IP2_HUMAN U3 small nucleolar RNA-interacting protein 2 (Gene Name=RRP9)

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