Structure of PDB 6t7t Chain SG

Receptor sequence

>6t7tSG (length=228) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVF
KISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGA
IVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKE
DDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQA
QREAAAEYAQLLAKRLSERKAEKAEIRK

3D structure

PDB

6t7t Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.

Chain

Resolution

3.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	SG	K2 N4 Q13 T15 S53 N56 Q59 G60 F61 Q65 G66 V67 R72 K74 C83 Y84 R85 R87 R88 D89 G90 R92 K93 R94 K95 S96 V108 K131 R132 L133 G134 P135 K136 R137 N139 N140 R154 V157 R159 R160 K164 Y169 K171 A172 P173 K174 I175 Q176 R177 L178 V179 Q182 R183 L184 Q185 R186 K187 R188 H189 Q190 R191 K194 V195 N197 A198 R202 L216 R227	K2 N4 Q13 T15 S53 N56 Q59 G60 F61 Q65 G66 V67 R72 K74 C83 Y84 R85 R87 R88 D89 G90 R92 K93 R94 K95 S96 V108 K131 R132 L133 G134 P135 K136 R137 N139 N140 R154 V157 R159 R160 K164 Y169 K171 A172 P173 K174 I175 Q176 R177 L178 V179 Q182 R183 L184 Q185 R186 K187 R188 H189 Q190 R191 K194 V195 N197 A198 R202 L216 R227

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0006412	translation
GO:0042254	ribosome biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0030686	90S preribosome
GO:0032040	small-subunit processome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Cellular Component

External links

PDB	RCSB:6t7t, PDBe:6t7t, PDBj:6t7t
PDBsum	6t7t
PubMed	31858614
UniProt	P0CX37\|RS6A_YEAST Small ribosomal subunit protein eS6A (Gene Name=RPS6A)

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