Structure of PDB 8k2a Chain SF

Receptor sequence
>8k2aSF (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
PRYELALILKAMQRPETAATLKRTIEALMDRGAIVRDLENLGERALPYRI
SAHSQQHNRGGYFLVDFYAPTAAVESMVEHLSRDIDVIRGNIVKHPLTQE
LKECEGIVPVPLAEKLYSTKKR
3D structure
PDB8k2a Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
ChainSF
Resolution2.9 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SF Y4 Y49 R50 S52 Q57 R90 I93 V94 K95 S119 Y3 Y48 R49 S51 Q56 R89 I92 V93 K94 S118
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8k2a, PDBe:8k2a, PDBj:8k2a
PDBsum8k2a
PubMed38942792
UniProtP82932|RT06_HUMAN Small ribosomal subunit protein bS6m (Gene Name=MRPS6)

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