Structure of PDB 8rxx Chain SC

Receptor sequence
>8rxxSC (length=212) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence]
GPLSKKRMIIRDGVFYAELFEFLKRELAEEGFSGVSYHVTTLRTEIVIKA
TKTREVLGVNGRRIRELTACIQQRFNYKEGKLQLYVERVEVRGLSAMAQV
ESLRFKLLSNLQVRRAAMGIIRYVMESGAKGCEVTVGGKIKGQRAKSMTF
RDGYMIKSGTAHKSFVDSACRHCYMRAGCIGVKVKIMLPGDSTGRNGPSE
PLPDVITVIEPK
3D structure
PDB8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
ChainSC
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SC P3 L4 S5 K6 K7 R8 R26 N77 K140 Q144 R145 A146 Y155 M156 K158 S159 G160 T161 H173 Y175 R177 A178 C180 G182 K184 P204 D205 P2 L3 S4 K5 K6 R7 R25 N76 K139 Q143 R144 A145 Y154 M155 K157 S158 G159 T160 H172 Y174 R176 A177 C179 G181 K183 P203 D204
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8rxx, PDBe:8rxx, PDBj:8rxx
PDBsum8rxx
PubMed38722744
UniProtQ4Q4A0

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