Structure of PDB 6xa1 Chain SC

Receptor sequence
>6xa1SC (length=220) Species: 9606 (Homo sapiens) [Search protein sequence]
EWMPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLK
IMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILA
KLSIVPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSAP
VPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKE
TVFTKSPYQEFTDHLVKTHT
3D structure
PDB6xa1 Selective inhibition of human translation termination by a drug-like compound.
ChainSC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna SC V112 Q113 K114 Q115 T116 R117 A118 Q120 K125 T185 R187 G189 S190 L192 R194 V205 S206 A207 Y223 T224 R227 T230 T232 N235 K238 V54 Q55 K56 Q57 T58 R59 A60 Q62 K67 T127 R129 G131 S132 L134 R136 V147 S148 A149 Y165 T166 R169 T172 T174 N177 K180
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

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Molecular Function
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Cellular Component
External links
PDB RCSB:6xa1, PDBe:6xa1, PDBj:6xa1
PDBsum6xa1
PubMed33009412
UniProtP15880|RS2_HUMAN Small ribosomal subunit protein uS5 (Gene Name=RPS2)

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