Structure of PDB 8gzu Chain S8

Receptor sequence
>8gzuS8 (length=218) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence]
GYIQRSNIHEEAPNTSVEAKHHNKTFYDPILDIDEDLKDDIRLYGRDKPD
ELDFTDVWESSYQNIICPEYFYHFWFCGIVYSFEPEWTINYPFEKGPLSP
LFRGEHALRRYPTGEERCIACKLCQSACPARAITIETEPRPDGSRRTVRY
DIDMTKCIYCGFCQEACPVDAIVEGPNYEQTAYLHEDLFYDKYKLLENGD
KWEPQIARNIEYLINQPL
3D structure
PDB8gzu Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
ChainS8
Resolution4.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 S8 C146 C175 I176 Y177 C178 G179 F180 C181 C128 C157 I158 Y159 C160 G161 F162 C163
BS02 SF4 S8 C136 I137 A138 C139 K140 C142 C185 P186 A189 C118 I119 A120 C121 K122 C124 C167 P168 A171
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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External links
PDB RCSB:8gzu, PDBe:8gzu, PDBj:8gzu
PDBsum8gzu
PubMed37248254
UniProtI7MDW5

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