Structure of PDB 8gzu Chain S1

Receptor sequence
>8gzuS1 (length=689) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence]
NKQIEIFIDGKPAKVDDSYTIFQACYENGVIVPRFCYHERLSVAGNCRMC
LVEVENVPKPVAACASQVVPGMKIKTKSEKTRIHRGNVMEFLLANHPLDC
PICDQGGECDLQDISSVYGYGISRYNEYKRAVEDKNYGPLVATSMNRCIH
CTRCVRFATQIAGVEDLGKTGRGKAAEIGTYVEKTFNTELSGNVVDVCPV
GALTNAPYAFTSRPWELKSFYTSDVFDTLGSAIQVDTRGPEIMRVLPRIH
EEINEEWISDKTRHAFDGLKRQRINSPMKRSKDGNYEDIFWEEAIQTISK
KCLNTPSDQIGAIIGEFADIESITALKDFLNRLDVDNFEVRQHGNLKVSP
DFRANYLMNSKITGVEDADVLLLVGCNPRYEAPVLNARILKSTRKNLKVF
NIGTNQDLNYKNVHLGNSTKVLKEIADGTHPFAERLKKAKLPMIMVGASA
LEREDGAELYNTLKVISNKTGVISEEKSWNGFNILHKEMGRINALELGIN
PTSVNKNAKLVFILGADNNLRPEDIPADAFVVYFGTHGDEGAYYADIILP
TAAYTEKNATWVNTEGRVQQGRLVVMPPGDAREDWQIIRALSEEAGVPLP
YDSLEELRYRVAELAPHLLKYDYIEPTIFGKVALSAQQGVKTTLSPTPIT
DYIDNFYMTDAISRASVTMAKCSTAFNHEKFSNFKNLAK
3D structure
PDB8gzu Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
ChainS1
Resolution4.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SF4 S1 D128 C129 Q134 C138 L140 V229 G230 D99 C100 Q105 C109 L111 V200 G201
BS02 SF4 S1 C177 I178 H179 C180 T181 R182 C183 I207 C227 A231 C148 I149 H150 C151 T152 R153 C154 I178 C198 A202
BS03 FES S1 C65 Y66 A73 G74 N75 C76 C36 Y37 A44 G45 N46 C47
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8gzu, PDBe:8gzu, PDBj:8gzu
PDBsum8gzu
PubMed37248254
UniProtQ23KA9

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