Structure of PDB 8gym Chain S1

Receptor sequence
>8gymS1 (length=689) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence]
NKQIEIFIDGKPAKVDDSYTIFQACYENGVIVPRFCYHERLSVAGNCRMC
LVEVENVPKPVAACASQVVPGMKIKTKSEKTRIHRGNVMEFLLANHPLDC
PICDQGGECDLQDISSVYGYGISRYNEYKRAVEDKNYGPLVATSMNRCIH
CTRCVRFATQIAGVEDLGKTGRGKAAEIGTYVEKTFNTELSGNVVDVCPV
GALTNAPYAFTSRPWELKSFYTSDVFDTLGSAIQVDTRGPEIMRVLPRIH
EEINEEWISDKTRHAFDGLKRQRINSPMKRSKDGNYEDIFWEEAIQTISK
KCLNTPSDQIGAIIGEFADIESITALKDFLNRLDVDNFEVRQHGNLKVSP
DFRANYLMNSKITGVEDADVLLLVGCNPRYEAPVLNARILKSTRKNLKVF
NIGTNQDLNYKNVHLGNSTKVLKEIADGTHPFAERLKKAKLPMIMVGASA
LEREDGAELYNTLKVISNKTGVISEEKSWNGFNILHKEMGRINALELGIN
PTSVNKNAKLVFILGADNNLRPEDIPADAFVVYFGTHGDEGAYYADIILP
TAAYTEKNATWVNTEGRVQQGRLVVMPPGDAREDWQIIRALSEEAGVPLP
YDSLEELRYRVAELAPHLLKYDYIEPTIFGKVALSAQQGVKTTLSPTPIT
DYIDNFYMTDAISRASVTMAKCSTAFNHEKFSNFKNLAK
3D structure
PDB8gym Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
ChainS1
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SF4 S1 H125 C129 C132 Q134 G135 C138 Q141 R176 V229 G230 H96 C100 C103 Q105 G106 C109 Q112 R147 V200 G201
BS02 SF4 S1 C177 I178 H179 C180 T181 R182 C183 C227 P228 A231 C148 I149 H150 C151 T152 R153 C154 C198 P199 A202
BS03 FES S1 R63 C65 Y66 C76 C79 C93 R34 C36 Y37 C47 C50 C64
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:0045333 cellular respiration
GO:1902600 proton transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8gym, PDBe:8gym, PDBj:8gym
PDBsum8gym
PubMed37248254
UniProtQ23KA9

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