Structure of PDB 8yvp Chain S

Receptor sequence
>8yvpS (length=212) Species: 10090 (Mus musculus) [Search protein sequence]
FSPYAFNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTV
IGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRF
FPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDN
QVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDVYTGDALRICIVTKE
GIREETVPLRKD
3D structure
PDB8yvp Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
ChainS
Resolution2.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L0D S Y97 F101 Y96 F100
Gene Ontology
Cellular Component
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005839 proteasome core complex
GO:0019774 proteasome core complex, beta-subunit complex

View graph for
Cellular Component
External links
PDB RCSB:8yvp, PDBe:8yvp, PDBj:8yvp
PDBsum8yvp
PubMed38906067
UniProtO09061|PSB1_MOUSE Proteasome subunit beta type-1 (Gene Name=Psmb1)

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