Structure of PDB 8y0w Chain S

Receptor sequence
>8y0wS (length=55) Species: 9606 (Homo sapiens) [Search protein sequence]
DGFDSRGKREFDRHSGSDRSGLKHEDKRGGSGSHNWGTVKDELTLDEWKA
IQNKD
3D structure
PDB8y0w dormant ribosome with eIF5A, eEF2 and SERBP1
ChainS
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna S R188 K190 R191 F193 D194 R195 H196 S197 G198 R201 G203 L204 K205 K209 R210 S213 G214 S215 H216 R6 K8 R9 F11 D12 R13 H14 S15 G16 R19 G21 L22 K23 K27 R28 S31 G32 S33 H34
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0030371 translation repressor activity
GO:0032183 SUMO binding
GO:0043022 ribosome binding
GO:0045296 cadherin binding
GO:0061770 translation elongation factor binding
Biological Process
GO:0006417 regulation of translation
GO:0017148 negative regulation of translation
GO:0030578 PML body organization
GO:0043488 regulation of mRNA stability
GO:0141014 ribosome hibernation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8y0w, PDBe:8y0w, PDBj:8y0w
PDBsum8y0w
PubMed38698775
UniProtQ8NC51|SERB1_HUMAN SERPINE1 mRNA-binding protein 1 (Gene Name=SERBP1)

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