Structure of PDB 8s8j Chain S

Receptor sequence

>8s8jS (length=145) Species: 284590 (Kluyveromyces lactis NRRL Y-1140)

SLVVQEQGSFQHILRLLNTNVDGNINVVYALTTIRGVGRRYANLVCKKAD
VDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQKDVNDGKDYHSL
ANNLESKLRDDLERLKKIRSHRGIRHFWGLRVRGQHTKTTGRRRA

3D structure

• PDB: 8s8j Structural basis of AUC codon discrimination during translation initiation in yeast.
• Chain: S
• Resolution: 4.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	S	I26 N27 Y30 R36 G37 V38 G39 R40 R41 Y42 W84 F85 N87 R88 Q89 L109 H122 R123 H127 R132 V133 R134 G135 Q136 H137 T138 K139 T140 T141 G142 R143 R144	I25 N26 Y29 R35 G36 V37 G38 R39 R40 Y41 W83 F84 N86 R87 Q88 L108 H121 R122 H126 R131 V132 R133 G134 Q135 H136 T137 K138 T139 T140 G141 R142 R143

External links

• PDB: RCSB:8s8j, PDBe:8s8j, PDBj:8s8j
• PDBsum: 8s8j
• PubMed: 39193907
• UniProt: Q6CWT9