Structure of PDB 8rw1 Chain S

Receptor sequence

>8rw1S (length=145) Species: 284590 (Kluyveromyces lactis NRRL Y-1140)

SLVVQEQGSFQHILRLLNTNVDGNINVVYALTTIRGVGRRYANLVCKKAD
VDLHKRAGELTQEELERIVQIMQNPTHYKIPAWFLNRQKDVNDGKDYHSL
ANNLESKLRDDLERLKKIRSHRGIRHFWGLRVRGQHTKTTGRRRA

3D structure

• PDB: 8rw1 Structural basis of AUC codon discrimination during translation initiation in yeast.
• Chain: S
• Resolution: 3.35 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	S	Y30 R36 G37 V38 G39 R40 R41 Y42 W84 F85 N87 Q89 K90 D112 H122 R123 R126 H127 L131 R132 V133 R134 G135 Q136 H137 T138 K139 T140 T141 G142 R143 R144	Y29 R35 G36 V37 G38 R39 R40 Y41 W83 F84 N86 Q88 K89 D111 H121 R122 R125 H126 L130 R131 V132 R133 G134 Q135 H136 T137 K138 T139 T140 G141 R142 R143

External links

• PDB: RCSB:8rw1, PDBe:8rw1, PDBj:8rw1
• PDBsum: 8rw1
• PubMed: 39193907
• UniProt: Q6CWT9