Structure of PDB 8pj2 Chain S

Receptor sequence

>8pj2S (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]

MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVV
RISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGC
IVDANLSVLNLVIVKKGEKDIPGLTDTTVPRRLGPKRASRIRKLFNLSKE
DDVRQYVVRKPLNKEGKKPRTKAPKIQRLVTPRVLQHKRRRIALKKQRTK
KNKEEAAEYAKLLAKRMKEAKEKRQEQIAK

3D structure

PDB

8pj2 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	S	K2 N4 S6 P8 G11 Q13 K14 L15 R31 S53 N56 K58 Q59 G60 F61 Q65 G66 R72 R74 L75 C83 Y84 R85 R87 R88 T89 G90 E91 R92 K93 R94 K95 S96 S107 V108 N110 R131 R132 L133 G134 P135 K136 R137 S139 R140 R154 R159 K160 L162 K164 K167 K168 R170 K172 A173 P174 K175 I176 Q177 R178 R183 V184 Q186 H187 K188 R189 R190 R191 K195 K196 R198 T199 K201 N202	K2 N4 S6 P8 G11 Q13 K14 L15 R31 S53 N56 K58 Q59 G60 F61 Q65 G66 R72 R74 L75 C83 Y84 R85 R87 R88 T89 G90 E91 R92 K93 R94 K95 S96 S107 V108 N110 R131 R132 L133 G134 P135 K136 R137 S139 R140 R154 R159 K160 L162 K164 K167 K168 R170 K172 A173 P174 K175 I176 Q177 R178 R183 V184 Q186 H187 K188 R189 R190 R191 K195 K196 R198 T199 K201 N202

External links

PDB	RCSB:8pj2, PDBe:8pj2, PDBj:8pj2
PDBsum	8pj2
PubMed
UniProt	P62753\|RS6_HUMAN Small ribosomal subunit protein eS6 (Gene Name=RPS6)

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