Structure of PDB 8ie3 Chain S

Receptor sequence
>8ie3S (length=135) Species: 9606 (Homo sapiens) [Search protein sequence]
VFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMP
FKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERK
AKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALL
3D structure
PDB8ie3 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
ChainS
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna S F3 R5 F17 D29 Q44 V45 R46 Q56 P65 H66 H69 K71 Y72 R74 R90 W91 K94 R98 M113 K114 K117 M118 N120 R121 K129 K132 F2 R4 F16 D28 Q43 V44 R45 Q55 P64 H65 H68 K70 Y71 R73 R89 W90 K93 R97 M112 K113 K116 M117 N119 R120 K128 K131
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0045296 cadherin binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ie3, PDBe:8ie3, PDBj:8ie3
PDBsum8ie3
PubMed37491604
UniProtP50914|RL14_HUMAN Large ribosomal subunit protein eL14 (Gene Name=RPL14)

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