Structure of PDB 8ewv Chain S

Receptor sequence
>8ewvS (length=146) Species: 9606 (Homo sapiens) [Search protein sequence]
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIH
SYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKE
RCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERI
3D structure
PDB8ewv DNA-encoded library (DEL)-enabled discovery of proximity inducing small molecules
ChainS
Resolution3.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X5K S R69 W88 Y98 P99 R107 I109 S111 Y112 H115 R9 W28 Y38 P39 R47 I49 S51 Y52 H55
External links
PDB RCSB:8ewv, PDBe:8ewv, PDBj:8ewv
PDBsum8ewv
PubMed37919549
UniProtP40337|VHL_HUMAN von Hippel-Lindau disease tumor suppressor (Gene Name=VHL)

[Back to BioLiP]