Structure of PDB 7pfx Chain S

Receptor sequence

>7pfxS (length=75) Species: 9606 (Homo sapiens) [Search protein sequence]

SGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLK
SLVSKGTLVQTKGTGASGSFKLNKK

3D structure

PDB

7pfx Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.

Chain

Resolution

4.3 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	S	P38 R53 S57 K63 R78 K96 G102 S103	P4 R19 S23 K29 R44 K62 G68 S69
BS02	dna	S	L58 K62 K80 A100 S101	L24 K28 K46 A66 S67

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0030527	structural constituent of chromatin
GO:0031490	chromatin DNA binding
GO:0031492	nucleosomal DNA binding
GO:0042826	histone deacetylase binding

	Biological Process
GO:0000122	negative regulation of transcription by RNA polymerase II
GO:0006325	chromatin organization
GO:0006334	nucleosome assembly
GO:0006357	regulation of transcription by RNA polymerase II
GO:0030261	chromosome condensation
GO:0045910	negative regulation of DNA recombination

External links