Structure of PDB 6zxf Chain S

Receptor sequence

>6zxfS (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]

SLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADID
LTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLAN
GLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR

3D structure

PDB

6zxf Structural basis for the final steps of human 40S ribosome maturation.

Chain

Resolution

3.7 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	S	R24 K25 F28 K34 G35 V36 G37 R55 W82 L84 N85 R86 Q87 K88 L107 D110 H120 R121 R124 H125 L129 R130 V131 R132 Q134 H135 T136 K137 T138 T139 R141	R23 K24 F27 K33 G34 V35 G36 R54 W81 L83 N84 R85 Q86 K87 L106 D109 H119 R120 R123 H124 L128 R129 V130 R131 Q133 H134 T135 K136 T137 T138 R140

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0014069	postsynaptic density
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0045202	synapse
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6zxf, PDBe:6zxf, PDBj:6zxf
PDBsum	6zxf
PubMed	33208940
UniProt	P62269\|RS18_HUMAN Small ribosomal subunit protein uS13 (Gene Name=RPS18)