Structure of PDB 5flx Chain S

Receptor sequence

>5flxS (length=139) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

VIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLT
KRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGL
DNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR

3D structure

PDB

5flx Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.

Chain

Resolution

3.9 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	S	R24 F28 I33 K34 G35 V36 G37 R38 Y40 W82 F83 L84 N85 R86 Q87 D89 H120 R121 R124 R130 V131 R132 G133 Q134 H135 T136 K137 T138 T139 G140 R141 R142	R21 F25 I30 K31 G32 V33 G34 R35 Y37 W79 F80 L81 N82 R83 Q84 D86 H117 R118 R121 R127 V128 R129 G130 Q131 H132 T133 K134 T135 T136 G137 R138 R139

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0019843	rRNA binding

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0014069	postsynaptic density
GO:0015935	small ribosomal subunit
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0045202	synapse
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:5flx, PDBe:5flx, PDBj:5flx
PDBsum	5flx
PubMed	26604301
UniProt	P62269\|RS18_HUMAN Small ribosomal subunit protein uS13 (Gene Name=RPS18)