Structure of PDB 4uuv Chain S

Receptor sequence
>4uuvS (length=95) Species: 9606 (Homo sapiens) [Search protein sequence]
ALQLWQFLVALLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPA
MNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCEPDALFSMAFPD
3D structure
PDB4uuv Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
ChainS
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna S Y392 R397 R400 K410 R415 Y416 Y53 R58 R61 K71 R76 Y77
BS02 dna S Q342 L343 W381 K385 R387 M390 D393 K394 S398 Y402 D434 Q3 L4 W42 K46 R48 M51 D54 K55 S59 Y63 D95
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4uuv, PDBe:4uuv, PDBj:4uuv
PDBsum4uuv
PubMed25866208
UniProtP43268|ETV4_HUMAN ETS translocation variant 4 (Gene Name=ETV4)

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