Structure of PDB 4kzx Chain S

Receptor sequence

>4kzxS (length=137) Species: 9986 (Oryctolagus cuniculus)

PEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKR
AGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDN
KLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRR

3D structure

• PDB: 4kzx The initiation of mammalian protein synthesis and mRNA scanning mechanism.
• Chain: S
• Resolution: 7.809 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	S	F28 G35 V36 G37 R38 R39 Y40 R55 W82 F83 L84 N85 Q87 K88 L107 D110 H120 R121 R124 L129 V131 R132 G133 H135 T136 K137 R141 R142	F23 G30 V31 G32 R33 R34 Y35 R50 W77 F78 L79 N80 Q82 K83 L102 D105 H115 R116 R119 L124 V126 R127 G128 H130 T131 K132 R136 R137

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0022626 cytosolic ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4kzx, PDBe:4kzx, PDBj:4kzx
• PDBsum: 4kzx
• PubMed: 23873042
• UniProt: G1TPG3|RS18_RABIT Small ribosomal subunit protein uS13 (Gene Name=RPS18)