Structure of PDB 1esv Chain S

Receptor sequence
>1esvS (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTCLYGDFFTGDAYVILKTV
QLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQG
FESATFLGYFKSGLKYKKGGVASGF
3D structure
PDB1esv Latrunculin alters the actin-monomer subunit interface to prevent polymerization.
ChainS
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA S D85 G90 A92 D85 G90 A92
BS02 CA S G41 D42 E73 V121 G41 D42 E73 V121
Gene Ontology
Molecular Function
GO:0051015 actin filament binding

View graph for
Molecular Function
External links
PDB RCSB:1esv, PDBe:1esv, PDBj:1esv
PDBsum1esv
PubMed10854330
UniProtP06396|GELS_HUMAN Gelsolin (Gene Name=GSN)

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