Structure of PDB 7d5t Chain RZ

Receptor sequence
>7d5tRZ (length=838) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
AFYVEVSRSDEIQKARIQLPVFGEEHKIMEAIHHNDVVIICGETGSGKTT
QVPQFLYEAGFGAEDSPDYPGMVGITQPRRVAAVSMAERVANELGDHGHK
VGYQIRFDSTAKEDTKVKFMTDGVLLREMMHDFKLTKYSSIIIDEAHERN
INTDILIGMLSRCVRLRAKLHKENPIEHKKLKLIIMSATLRVSDFSENKT
LFPIAPPVLQVDARQFPVSIHFNRRTAFNYTDEAFRKTCKIHQKLPPGAI
LVFLTGQQEITHMVKRLRKEFPFKKNSKYNKDLETPVSKMGINSKTTDLE
AEDIDFSVQVIDQDKFKSAIRYEEEEEEGFEEVLTEGQTANDPLYVLPLY
SLLPTKEQMRVFQKPPQGSRLCIVATNVAETSLTIPGVRYVVDSGRSKER
KYNESNGVQSFEVGWVSKASANQRSGRAGRTGPGHCYRLYSSAVFEHDFE
QFKPEILRMPVESIVLQMKSMAIHNIINFPFPTPPDRVALSKAIQLLQYL
GALDNKEMITEDGKKMSLFPLSPRFSKMLLVSDEKACLPYIVAIVSALSV
GDPFINEFELGPELKKELRSKFYKSRSQFSKLDKFSDVFRLLSVVSAMDY
VPKEQKEIFMKKNFLRGKLMEEIVKLRKQLMYIIKSNTSKENIAVVIRNE
DLKSDIPSVIQIKLLKQMICAGFVDHVAVRADVLFPDDAKITNRTSIINI
PYIPVLATRTPNIEDCFVYIHPTSILNNLGEMPPKYMLYYSLHLGGNNKT
RMNTLCDIASTPLANIARKGLLLTYSKPLTGQGLKTVNLSPTERYCYVVP
RFGSTVDNDLKIGWDLNPIAVHQKKQKGQWTVIKFITR
3D structure
PDB7d5t Cryo-EM structure of 90S preribosome with inactive Utp24 (state F1)
ChainRZ
Resolution6.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP RZ E415 T416 G417 S418 G419 K420 T421 T422 M458 E460 R461 F747 T769 P771 E43 T44 G45 S46 G47 K48 T49 T50 M86 E88 R89 F362 T384 P386
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0022613 ribonucleoprotein complex biogenesis
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7d5t, PDBe:7d5t, PDBj:7d5t
PDBsum7d5t
PubMed
UniProtQ04217|DHR1_YEAST Probable ATP-dependent RNA helicase DHR1 (Gene Name=ECM16)

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