Structure of PDB 6oxa Chain RZ

Receptor sequence
>6oxaRZ (length=183) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSL
HASDLKLPPGVELAVSPEETIAAVVPPEDVEKL
3D structure
PDB6oxa Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
ChainRZ
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna RZ I146 S149 H151 E169 P176 I146 S149 H151 E169 P176
BS02 rna RZ P15 R19 Y29 R31 N34 K36 R72 Q73 E84 H85 F89 P15 R19 Y29 R31 N34 K36 R72 Q73 E84 H85 F89
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:6oxa, PDBe:6oxa, PDBj:6oxa
PDBsum6oxa
PubMed31501867
UniProtQ5SHZ1|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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