Structure of PDB 6bz7 Chain RU

Receptor sequence

>6bz7RU (length=117) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]

PRAKTGVVRRRKHKKILKLAKGYWGLRSKSFRKARETLFAAGNYAYAHRK
RRKRDFRRLWIVRINAACRQHGLNYSTFIHGLKKAGIEVDRKNLADLAVR
EPQVFAELVERAKAAQG

3D structure

PDB

6bz7 Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.

Chain

Resolution

3.68 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	RU	P2 R3 A4 K5 T6 V8 R10 R11 K13 H14 K15 K16 K19 G23 Y24 W25 G26 L27 R28 S29 S31 F32 R33 K34 R36 E37 A42 Y45 Y47 H49 R50 K51 R52 R53 K54 R55 F57 R58 W61 I62 N66 N75 Y76 S77 H81 R92 K93	P1 R2 A3 K4 T5 V7 R9 R10 K12 H13 K14 K15 K18 G22 Y23 W24 G25 L26 R27 S28 S30 F31 R32 K33 R35 E36 A41 Y44 Y46 H48 R49 K50 R51 R52 K53 R54 F56 R57 W60 I61 N65 N74 Y75 S76 H80 R91 K92
BS02	MG	RU	Y47 K51	Y46 K50

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6bz7, PDBe:6bz7, PDBj:6bz7
PDBsum	6bz7
PubMed	30476222
UniProt	P60491\|RL20_THET8 Large ribosomal subunit protein bL20 (Gene Name=rplT)