Structure of PDB 7qvp Chain RT

Receptor sequence

>7qvpRT (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]

PGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN
WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVAR
RVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAN

3D structure

PDB

7qvp A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.

Chain

Resolution

3.0 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	RT	P2 V4 K7 Q12 V15 W33 V37 K41 K43 E44 A46 P47 Y48 R56 S59 R62 H63 R67 G71 G73 S74 K77 I78 R82 R84 G86 V87 M88 P89 H91 F92 S96 K97 S98 R101 R102 G119 G120 R121 P125 Q128 R129 D132 R133	P1 V3 K6 Q11 V14 W32 V36 K40 K42 E43 A45 P46 Y47 R55 S58 R61 H62 R66 G70 G72 S73 K76 I77 R81 R83 G85 V86 M87 P88 H90 F91 S95 K96 S97 R100 R101 G118 G119 R120 P124 Q127 R128 D131 R132

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

External links