Structure of PDB 6buw Chain RT

Receptor sequence
>6buwRT (length=137) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MNRGALIKLVESRYVRTDLPEFRPGDTVRVSYKVKEGNRTRIQDFEGIVI
RIRRNGFNTTFTVRKVSYGVGVERIFPLHSPLIQKIDIVQRGRARRAKLY
FIRNLSDREIRRKLRADRKRIDQDRAAERAAKEEAQK
3D structure
PDB6buw Ribosomal ambiguity (ram) mutations promote the open (off) to closed (on) transition and thereby increase miscoding.
ChainRT
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna RT R41 D107 R108 R112 R118 D122 R125 R41 D107 R108 R112 R118 D122 R125
BS02 rna RT N2 R3 A5 R23 R51 R53 R54 N55 G56 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 K119 N2 R3 A5 R23 R51 R53 R54 N55 G56 N58 T60 I75 R93 R95 R96 A97 K98 Y100 F101 K113 K119
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:6buw, PDBe:6buw, PDBj:6buw
PDBsum6buw
PubMed30476222
UniProtP60490|RL19_THET8 Large ribosomal subunit protein bL19 (Gene Name=rplS)

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