Structure of PDB 6lqu Chain RO

Receptor sequence
>6lquRO (length=525) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DIAKRLTAAGDRKQYNSIIKLINELVIPENVTQLEEDETEKNLRFLVMSL
FQIFRKLFSRGDLTLPSSKKSTLEKEQFVNWCRKVYEAFKTKLLAIISDI
PFETSLGLDSLDVYLQLAELESTHFASEKGAPFFPNKTFRKLIIALWSSN
MGEIEDVKSSGASENLIIVEFTEKYYTKFADIQYYFQSEFNQLLEDPAYQ
DLLLKNVGKWLALVNHDKHCSSVDADLEIFVPNPPQAIENESKFKSNFEK
NWLSLLNGQLSLQQYKSILLILHKRIIPHFHTPTKLMDFLTDSYNLQSSN
KNAGVVPILALNGLFELMKRFNLEYPNFYMKLYQIINPDLMHVKYRARFF
RLMDVFLSSTHLSAHLVASFIKKLARLTLESPPSAIVTVIPFIYNLIRKH
PNCMIMLHNPAFISNPFQTPDQVANLKTLKENYVDPFDVHESDPELTHAL
DSSLWELASLMEHYHPNVATLAKIFAQPFKKLSYNMEDFLDWNYDSLLNA
ESSRKLKTLPTLEFEAFTNVFDNED
3D structure
PDB6lqu Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
ChainRO
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna RO S136 P244 Q245 H290 S127 P235 Q236 H281
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0030686 90S preribosome
GO:0030688 preribosome, small subunit precursor
GO:0030692 Noc4p-Nop14p complex
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lqu, PDBe:6lqu, PDBj:6lqu
PDBsum6lqu
PubMed32943522
UniProtQ06512|NOC4_YEAST Nucleolar complex protein 4 (Gene Name=NOC4)

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