Structure of PDB 7qvp Chain RN

Receptor sequence

>7qvpRN (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]

GRMHAPGKGLSQSALPYRRSVPTWLKLTSDDVKEQIYKLAKKGLTPSQIG
VILRDSHGVAQVRFVTGNKILRILKSKGLAPDLPEDLYHLIKKAVAVRKH
LERNRKDKDAKFRLILIESRIHRLARYYKTKRVLPPNWKYESSTASALVA

3D structure

PDB

7qvp A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.

Chain

Resolution

3.0 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	RN	H123 K140	H122 K139
BS02	rna	RN	G2 R3 M4 H5 G8 K9 G10 L11 S12 S14 A15 L16 P17 R20 S48 R55 A61 Q62 R64 N69 K70 L72 R73 K76 E86 D87 H90 K94 H101 R104 N105 D108 K109 K112 F113 R114 L117 S120 R121 R124 R127 Y128	G1 R2 M3 H4 G7 K8 G9 L10 S11 S13 A14 L15 P16 R19 S47 R54 A60 Q61 R63 N68 K69 L71 R72 K75 E85 D86 H89 K93 H100 R103 N104 D107 K108 K111 F112 R113 L116 S119 R120 R123 R126 Y127

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome
GO:0070181	small ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7qvp, PDBe:7qvp, PDBj:7qvp
PDBsum	7qvp
PubMed	36302773
UniProt	A0A663F1C0

[Back to BioLiP]