Structure of PDB 6ke6 Chain RN

Receptor sequence

>6ke6RN (length=587) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

QLKNLKAALKARGNPFEIKAARNKRIAVGKPGISKQIGEEQRKRAFEARK
MMKNKRGGVIDKRPQRKKTKAEVMKEVIAKSKFYKQERQKAQGIMEDQID
NLDDNFEDVMSELMMTDLDKEYDIKVKELQLDKRAAPSDRTKTEEEKNAE
AEEKKRELEQQRLDRMNGRTHDALLDQVKKLDLDDHPKIVKNIIKAYQPK
LAEGNKEKLGKFTAVLLRHIIFLSNQNYLKNVQSFKRTQNALISILKSLS
EKYNRELSEECRDYINEMQARYKKNHFDALSNGDLVFFSIIGILFSTSDQ
YHLVITPALILMSQFLEQIKFNSLKRIAFGAVLVRIVSQYQRISKRYIPE
VVYFFQKILLTFIVEPLDFENIRLDSYELGLPLDVDFTKKRSTIIPLHTL
STMDTEAHPVDQCVSVLLNVMESLDATISTVWKSLPAFNEIILPIQQLLS
AYTSKYSDFEKPRNILNKVEKLTKFTEHIPLALQNHKPVSIPTHAPKYEE
NFNPDKKSYDPDRTRSEINKMKAQLKKERKFTMKEIRKDAKFEARQRIEE
KNKESSDYHAKMAHIVNTINTEEGAEKNKYERERKLR

3D structure

PDB

6ke6 3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome

Chain

Resolution

3.4 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	RN	T790 A794 N797	T571 A575 N578
BS02	rna	RN	K7 K61 K66 V81 G82 K83 P84 S87 K205 E209 E213 A216 L414 E416 K726 P730 S735 N738 K739 A742 Q743 K746 K749 H778 A779 A782 H783	K3 K19 K24 V28 G29 K30 P31 S34 K68 E72 E76 A79 L201 E203 K507 P511 S516 N519 K520 A523 Q524 K527 K530 H559 A560 A563 H564

Gene Ontology

	Molecular Function
GO:0005515	protein binding
GO:0034511	U3 snoRNA binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0030490	maturation of SSU-rRNA
GO:0042254	ribosome biogenesis
GO:0042274	ribosomal small subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0030686	90S preribosome
GO:0030688	preribosome, small subunit precursor
GO:0030692	Noc4p-Nop14p complex
GO:0032040	small-subunit processome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6ke6, PDBe:6ke6, PDBj:6ke6
PDBsum	6ke6
PubMed
UniProt	Q99207\|NOP14_YEAST Nucleolar complex protein 14 (Gene Name=NOP14)

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