Structure of PDB 6lqt Chain RK

Receptor sequence
>6lqtRK (length=360) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KYTTFQGSQNFRLRIVLATLSGKPIKIEKIRSGDLNPGLKDYEVSFLRLI
ESVTNGSVIEISYTGTTVIYRPGIIVGGASTHICPSSKPVGYFVEPMLYL
APFSKKKFSILFKGITASHNDAGIEAIKWGLMPVMEKFGVRECALHTLKR
GSPPLGGGEVHLVVDSLIAQPITMHEIDRPIISSITGVAYSTRVSPSLVN
RMIDGAKKVLKNLQCEVNITADVWRGENSGKSPGWGITLVAQSKQKGWSY
FAEDIGDAGSIPEELGEKVACQLLEEISKSAAVGRNQLPLAIVYMVIGKE
DIGRLRINKEQIDERFIILLRDIKKIFNTEVFLKPVDEADNEDMIATIKG
IGFTNTSKKI
3D structure
PDB6lqt Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
ChainRK
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna RK R199 S201 R231 G232 R193 S195 R225 G226
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003963 RNA-3'-phosphate cyclase activity
GO:0004521 RNA endonuclease activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
Biological Process
GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:2000232 regulation of rRNA processing
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lqt, PDBe:6lqt, PDBj:6lqt
PDBsum6lqt
PubMed32943522
UniProtQ08096|RCL1_YEAST RNA 3'-terminal phosphate cyclase-like protein (Gene Name=RCL1)

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