Structure of PDB 4lsk Chain RG

Receptor sequence

>4lskRG (length=181) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]

PLDVALKRKYYEEVRPELIRRFGYQNVWEVPRLEKVVINQGLGEAKEDAR
ILEKAAQELALITGQKPAVTRAKKSISNFKLRKGMPIGLRVTLRRDRMWI
FLEKLLNVALPRIRDFRGLNPNSFDGRGNYNLGLREQLIFPEITYDMVDA
LRGMDIAVVTTAETDEEARALLELLGFPFRK

3D structure

PDB

4lsk Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops.

Chain

Resolution

3.48001 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	RG	N40 G42 G44 E45 K47 T71 A73 K74 N79 F80 L82 I88 R91 R128 N132 G134 L152	N39 G41 G43 E44 K46 T70 A72 K73 N78 F79 L81 I87 R90 R127 N131 G133 L151
BS02	rna	RG	P2 N27 V28 W29 E30 R33 Q66 K67 P68 A69 V70 R72 R91 V92 T93 R95 R96 R98	P1 N26 V27 W28 E29 R32 Q65 K66 P67 A68 V69 R71 R90 V91 T92 R94 R95 R97

Gene Ontology

	Molecular Function
GO:0000049	tRNA binding
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:4lsk, PDBe:4lsk, PDBj:4lsk
PDBsum	4lsk
PubMed	25128388
UniProt	Q5SHQ0\|RL5_THET8 Large ribosomal subunit protein uL5 (Gene Name=rplE)

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