Structure of PDB 6lqq Chain RB

Receptor sequence

>6lqqRB (length=134) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

FEDRFDAREHKDRSNKSRMQAMEEYIRESSDQPDWSASIGADIVNHGRGG
IKSLRDTEKERRVTSFEEDNFTRLNITNKAEKRKQKQRERNARMNVIGGE
DFGIFSSKRKLEDSTSRRGAKKTRSAWDRAQRRL

3D structure

PDB

6lqq Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.

Chain

Resolution

4.1 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	RB	F224 R227 R231 N238 K239 R241 Q243 E246 R271 R278 E281 K309 R316 I327 S330 K331 R332	F1 R4 R8 N15 K16 R18 Q20 E23 R48 R55 E58 K86 R93 I104 S107 K108 R109

Gene Ontology

	Molecular Function
GO:0003674	molecular_function
GO:0005515	protein binding

	Biological Process
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0008150	biological_process
GO:0030490	maturation of SSU-rRNA
GO:0042254	ribosome biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005732	sno(s)RNA-containing ribonucleoprotein complex
GO:0030532	small nuclear ribonucleoprotein complex
GO:0032040	small-subunit processome
GO:1990904	ribonucleoprotein complex

External links

PDB	RCSB:6lqq, PDBe:6lqq, PDBj:6lqq
PDBsum	6lqq
PubMed	32943522
UniProt	P40079\|LCP5_YEAST U3 small nucleolar ribonucleoprotein protein LCP5 (Gene Name=LCP5)