Structure of PDB 9bln Chain R

Receptor sequence

>9blnR (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]

GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGG
NKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCI
VLIDSTPYRQWYESHYALPLGRKEEEILNKKRSKKIQKKYDERKKNAKIS
SLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKG

3D structure

PDB

9bln Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.

Chain

Resolution

3.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	R	G2 I3 R5 N7 H9 K10 R11 R12 T14 G16 K19 Y21 K23 K24 R25 K26 Y27 L29 R31 P32 A33 A34 R41 R42 H44 T45 R47 V48 R49 G50 K53 K54 Y55 R56 L58 R59 N64 S66 C71 C72 T73 R74 K75 S86 V97 K98 N99 K143 K144 I145 K147 K148 Y149 A176 R178 G180 Q181 R184 D186 G187	G1 I2 R4 N6 H8 K9 R10 R11 T13 G15 K18 Y20 K22 K23 R24 K25 Y26 L28 R30 P31 A32 A33 R40 R41 H43 T44 R46 V47 R48 G49 K52 K53 Y54 R55 L57 R58 N63 S65 C70 C71 T72 R73 K74 S85 V96 K97 N98 K134 K135 I136 K138 K139 Y140 A167 R169 G171 Q172 R175 D177 G178

External links

PDB	RCSB:9bln, PDBe:9bln, PDBj:9bln
PDBsum	9bln
PubMed	39117603
UniProt	P62241\|RS8_HUMAN Small ribosomal subunit protein eS8 (Gene Name=RPS8)

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