Structure of PDB 9bkd Chain R

Receptor sequence

>9bkdR (length=198) Species: 9606 (Homo sapiens) [Search protein sequence]

GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGG
NKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCI
VLIDSTPYRQWYESHYALPLGRKEEEILNKKRSKKIQKKYDERKKNAKIS
SLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKG

3D structure

PDB

9bkd Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	R	G2 I3 R5 N7 H9 K10 R11 R12 K13 T14 K19 Y21 K23 K24 R25 K26 Y27 L29 R31 A33 A34 R41 R42 I43 H44 T45 R47 V48 R49 G50 N52 K53 K54 Y55 R56 L58 R59 N64 S66 C72 T73 R74 S86 K98 N99 K143 K144 I145 K147 K148 Y149 R152 R178 Q181 G183 R184 D186	G1 I2 R4 N6 H8 K9 R10 R11 K12 T13 K18 Y20 K22 K23 R24 K25 Y26 L28 R30 A32 A33 R40 R41 I42 H43 T44 R46 V47 R48 G49 N51 K52 K53 Y54 R55 L57 R58 N63 S65 C71 T72 R73 S85 K97 N98 K134 K135 I136 K138 K139 Y140 R143 R169 Q172 G174 R175 D177

External links

PDB	RCSB:9bkd, PDBe:9bkd, PDBj:9bkd
PDBsum	9bkd
PubMed	39117603
UniProt	P62241\|RS8_HUMAN Small ribosomal subunit protein eS8 (Gene Name=RPS8)

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