Structure of PDB 8zps Chain R

Receptor sequence
>8zpsR (length=289) Species: 9606 (Homo sapiens) [Search protein sequence]
QLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLA
LSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLT
TIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVEL
KPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLR
NRVADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYA
FGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLV
3D structure
PDB8zps Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
ChainR
Resolution2.97 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R Q54 T117 Y120 P142 V145 Y146 P205 E212 Y225 L229 R301 P310 Q317 H321 Q1 T64 Y67 P89 V92 Y93 P152 E159 Y172 L176 R239 P248 Q255 H259
External links
PDB RCSB:8zps, PDBe:8zps, PDBj:8zps
PDBsum8zps
PubMed39223120
UniProtP49683|PRLHR_HUMAN Prolactin-releasing peptide receptor (Gene Name=PRLHR)

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