Structure of PDB 8xve Chain R

Receptor sequence
>8xveR (length=308) Species: 1502,9606 [Search protein sequence]
SPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNG
PNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASV
GITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVP
EAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLP
LAITAFFYTLMTCEMLRKKLNDHLKQRREVAKTVFCLVLVFALCWLPLHL
SRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSK
RFKNCFKS
3D structure
PDB8xve Structural basis of antagonist selectivity in endothelin receptors.
ChainR
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R N158 K161 E165 Q181 K182 Y247 I254 P259 K273 L339 R343 K346 Y350 L361 L365 D368 Y369 N73 K76 E80 Q96 K97 Y162 I169 P174 K188 L248 R252 K255 Y259 L270 L274 D277 Y278
External links
PDB RCSB:8xve, PDBe:8xve, PDBj:8xve
PDBsum8xve
PubMed39075075
UniProtP24530|EDNRB_HUMAN Endothelin receptor type B (Gene Name=EDNRB);
Q59310

[Back to BioLiP]