Structure of PDB 8t3o Chain R

Receptor sequence
>8t3oR (length=297) Species: 9606 (Homo sapiens) [Search protein sequence]
RTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRR
GATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLS
GSVTILTLAAVSLERMVCIVHLQRGPGRRARAVLLALIWGYSAVAALPLC
VFFRVVPQRISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKIL
QITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPII
ITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRN
3D structure
PDB8t3o Structural basis for the ligand recognition and signaling of free fatty acid receptors.
ChainR
Resolution3.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YN9 R F88 F115 M118 T119 S123 L173 D208 F211 I280 I284 I287 L288 F67 F94 M97 T98 S102 L149 D177 F180 I249 I253 I256 L257
BS02 2Y5 R L79 C83 L86 L58 C62 L65
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8t3o, PDBe:8t3o, PDBj:8t3o
PDBsum8t3o
PubMed38198545
UniProtQ5NUL3|FFAR4_HUMAN Free fatty acid receptor 4 (Gene Name=FFAR4)

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