Structure of PDB 8sg1 Chain R

Receptor sequence
>8sg1R (length=279) Species: 9606 (Homo sapiens) [Search protein sequence]
ARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVAD
FLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISS
DRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHG
KISCFNNFSLSDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQ
RNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGL
PLATALAIANSCMNPILYVFMGQDFKKFK
3D structure
PDB8sg1 Cryo-EM structure of CMKLR1 signaling complex
ChainR
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide R H95 Y103 I120 R178 F190 N191 H217 R224 Y276 H60 Y68 I85 R143 F155 N156 H169 R176 Y228
BS02 CLR R K260 I267 K212 I219
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8sg1, PDBe:8sg1, PDBj:8sg1
PDBsum8sg1
PubMed38055679
UniProtQ99788|CML1_HUMAN Chemerin-like receptor 1 (Gene Name=CMKLR1)

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