Structure of PDB 8rkv Chain R

Receptor sequence

>8rkvR (length=504) Species: 34078 (Scytonema hofmannii)

KNVIATQLSEEAQVKLEVIQSLLEPCDRTTYGQKLREAAEKLNVSLRTVQ
RLVKNWEQDGLVGLTQTSRADKGKHRIGEFWENFITKTYKEGNKGSKRMT
PKQVALRVEAKARELKDSKPPNYKTVLRVLAPILEKQQKAKSIRSPGWRG
TTLSVKTREGKDLSVDYSNHVWQCDHTRVDVLLVDQHGEILSRPWLTTVI
DTYSRCIMGINLGFDAPSSGVVALALRHAILPKRYGSEYKLHCEWGTYGK
PEHFYTDGGKDFRSNHLSQIGAQLGFVCHLRDRPSEGGVVERPFKTLNDQ
LFSTLPGYTGSNVQERPEDAEKDARLTLRELEQLLVRYIVDRYNQSIDAR
MGDQTRFERWEAGLPTVPVPIPERDLDICLMKQSRRTVQRGGCLQFQNLM
YRGEYLAGYAGETVNLRFDPRDITTILVYRQENNQEVFLTRAHAQGLETE
QLALDEAEAASRRLRTAGKTISNQSLLQEVVDRDAKERQKLEQTVLRSAA
VDES

3D structure

• PDB: 8rkv Conformational landscape of the type V-K CRISPR-associated transposon integration assembly.
• Chain: R
• Resolution: 3.11 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	R	G289 R416 T417 Q425 F426 Q427 N428 R492 R495	G259 R386 T387 Q395 F396 Q397 N398 R462 R465
BS02	dna	R	Q80 R81 K84 S98 R99 K102 G103 K104 R106 I107 N152 K154 R158 A246 S248 S249 K290 N295 R420	Q50 R51 K54 S68 R69 K72 G73 K74 R76 I77 N122 K124 R128 A216 S218 S219 K260 N265 R390
BS03	dna	R	S75 R77 T78 R81 Q96 R99 R106 K132 Y153 K154 L157	S45 R47 T48 R51 Q66 R69 R76 K102 Y123 K124 L127
BS04	dna	R	S175 P176 G177 W178 R179 S315 G318 R322 T326 Q330 A379 R380 R386	S145 P146 G147 W148 R149 S285 G288 R292 T296 Q300 A349 R350 R356
BS05	dna	R	R174 T207 R223 W225 E321 K325 V343 R346	R144 T177 R193 W195 E291 K295 V313 R316
BS06	MG	R	D205 D287	D175 D257

External links

• PDB: RCSB:8rkv, PDBe:8rkv, PDBj:8rkv
• PDBsum: 8rkv
• PubMed: 38834066
• UniProt: A0A979HMQ2