Structure of PDB 8kgg Chain R

Receptor sequence
>8kggR (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
CNVTNVKFQYSLYATTYILIFIPGLLANSAALWVLCRFISKKNKAIIFMI
NLSVADLAHVLSLPLRIYYYISHHWPFQRALCLLCFYLKYLNMYASICFL
TCISLQRCFFLLKPFRARDWKRRYDVGISAAIWIVVGTACLPFPILRSTD
LNNNKSCFADLGYKQMNAVALVGMITVAELAGFVIPVIIIAWCTWKTTIS
LRQPPMAFQGISERQKALRMVFMCAAVFFICFTPYHINFIFYTMVKETII
SSCPVVRIALYFHPFCLCLASLCCLLDPILYYFMASEFRD
3D structure
PDB8kgg LPS-bound P2Y10 in complex with G13
ChainR
Resolution3.06 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WJS R R90 Y114 F167 R171 A183 M198 A202 H287 L291 R66 Y90 F143 R147 A159 M174 A178 H263 L267
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0035025 positive regulation of Rho protein signal transduction
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8kgg, PDBe:8kgg, PDBj:8kgg
PDBsum8kgg
PubMed39265572
UniProtO00398|P2Y10_HUMAN Putative P2Y purinoceptor 10 (Gene Name=P2RY10)

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