Structure of PDB 8iwe Chain R

Receptor sequence
>8iweR (length=296) Species: 10090 (Mus musculus) [Search protein sequence]
CIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLV
ASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLF
HLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTG
ANEEGIEELVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFL
VAKYQARKIEGYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAY
MNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGK
3D structure
PDB8iwe Structural basis of amine odorant perception by a mammal olfactory receptor.
ChainR
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SPD R D112 T113 F168 Y274 V300 D91 T92 F147 Y241 V267
Gene Ontology
Molecular Function
GO:0001594 trace-amine receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0008227 G protein-coupled amine receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8iwe, PDBe:8iwe, PDBj:8iwe
PDBsum8iwe
PubMed37225986
UniProtQ5QD04|TAAR9_MOUSE Trace amine-associated receptor 9 (Gene Name=Taar9)

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