Structure of PDB 8ikh Chain R

Receptor sequence
>8ikhR (length=265) Species: 9606 (Homo sapiens) [Search protein sequence]
ECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHF
IGSLAVADLLGSVIFVYSFIDFHRKDSRNVFLFKLGGVTASFTASVGSLF
LTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCI
DETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGARMDIRLAK
TLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVN
PIIYALRSKDLRHAF
3D structure
PDB8ikh Cryo-EM structure of human receptor with G proteins
ChainR
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Q2L R L165 F191 G194 G195 I245 L60 F83 G86 G87 I137
External links
PDB RCSB:8ikh, PDBe:8ikh, PDBj:8ikh
PDBsum8ikh
PubMed38830102
UniProtP21554|CNR1_HUMAN Cannabinoid receptor 1 (Gene Name=CNR1)

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