Structure of PDB 8hqm Chain R

Receptor sequence
>8hqmR (length=307) Species: 562,9606 [Search protein sequence]
SFEESRIVLVVVYSAVCTLGVPANCLTAWLALLQVLQGNVLAVYLLCLAL
CELLYTGTLPLWVIYIRNQHRWTLGLLACKVTAYIFFCNIYVSILFLCCI
SCDRFVAVVYALESRGRRRRRTAILISACIFILVGIVHYPVFQTEDKETC
FDMLQMDSRIAGYYYARFTVGFAIPLSIIAFTNHRIFRSIKQSMGLSAAQ
KAKVKHSAIAVVVIFLVCFAPYHLVLLVKAAAFSYYRGAMCGLEERLYTA
SVVFLCLSTVNGVADPIIYVLATDHSRQEVSRIHKGWKEWSMKTDVTRLT
HSRDTEE
3D structure
PDB8hqm Functional screening and rational design of compounds targeting GPR132 to treat diabetes.
ChainR
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 140 R H106 E184 T185 Q191 E283 Y287 H70 E148 T149 Q155 E244 Y248
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0007186 G protein-coupled receptor signaling pathway
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0022900 electron transport chain
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:8hqm, PDBe:8hqm, PDBj:8hqm
PDBsum8hqm
PubMed37770763
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
Q9UNW8

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