Structure of PDB 8hnk Chain R

Receptor sequence
>8hnkR (length=297) Species: 562,9606,727944 [Search protein sequence]
SPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTD
TFLLHLAVADTLLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGA
LLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIF
LSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHIL
AVLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARN
CGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRL
3D structure
PDB8hnk Structural insights into the activation and inhibition of CXC chemokine receptor 3
ChainR
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.13.12.13: Oplophorus-luciferin 2-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR R G122 F187 G83 F148
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0009055 electron transfer activity
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019956 chemokine binding
GO:0019957 C-C chemokine binding
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0001525 angiogenesis
GO:0002685 regulation of leukocyte migration
GO:0006915 apoptotic process
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0019722 calcium-mediated signaling
GO:0022900 electron transport chain
GO:0030155 regulation of cell adhesion
GO:0060326 cell chemotaxis
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8hnk, PDBe:8hnk, PDBj:8hnk
PDBsum8hnk
PubMed38177682
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P49682;
Q9GV45|LUCI_OPLGR Oplophorus-luciferin 2-monooxygenase catalytic subunit

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