Structure of PDB 8esc Chain R

Receptor sequence
>8escR (length=417) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
VYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIF
SEQSIGIPRKDYELKPIIENGLVIDWDTAQEQWQWALQNELYLNSNSGIP
ALLTEPVWNSTENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLV
VDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPKEIIPLF
AIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTLEE
TKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLPKEDDIPANWPRS
NSGVVKTWELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGLSD
RLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQLWVGK
KEYEEVGVERLLNDRFR
3D structure
PDB8esc Structure and flexibility of the yeast NuA4 histone acetyltransferase complex.
ChainR
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP R G22 S23 Y24 G161 H162 Q240 K243 E244 G413 T414 Q449 G15 S16 Y17 G154 H155 Q233 K236 E237 G341 T342 Q377
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042393 histone binding
Biological Process
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0051382 kinetochore assembly
Cellular Component
GO:0000785 chromatin
GO:0000812 Swr1 complex
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0031011 Ino80 complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0043232 intracellular non-membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8esc, PDBe:8esc, PDBj:8esc
PDBsum8esc
PubMed36263929
UniProtP80428|ARP4_YEAST Actin-related protein 4 (Gene Name=ARP4)

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