Structure of PDB 7xp6 Chain R

Receptor sequence
>7xp6R (length=283) Species: 9606,203119 [Search protein sequence]
TFLPIIFSILIVVTFVIGNFANGFIALVNSIEWFKRQKISFADQILTALA
VSRVGLLWVLVLNWYATELNPAFNSIEVRITAYNVWAVINHFSNWLATSL
SIFYLLKIANFSNLIFLHLKRRVKSVVLVILLGPLLFLVCHLFVINMNQI
IWTKYLSNTTVTILANLVPFTLTLISFLLLICSLCKHLKKMQLHGKGSQD
PSMKVHIKALQTVTSFLLLCAIYFLSIIMSVWSFESLENKPVFMFCEAIA
FSYPSTHPFILIWGNKKLKQTFLSVLWHVRYWV
3D structure
PDB7xp6 Structural basis for strychnine activation of human bitter taste receptor TAS2R46.
ChainR
Resolution3.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
3.2.1.4: cellulase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SY9 R N65 Y85 W88 E265 N63 Y83 W86 E247
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004930 G protein-coupled receptor activity
GO:0033038 bitter taste receptor activity
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0007186 G protein-coupled receptor signaling pathway
GO:0050909 sensory perception of taste
Cellular Component
GO:0005886 plasma membrane
GO:0005929 cilium
GO:0016020 membrane
GO:0060170 ciliary membrane

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Cellular Component
External links
PDB RCSB:7xp6, PDBe:7xp6, PDBj:7xp6
PDBsum7xp6
PubMed36108005
UniProtP16218|GUNH_ACET2 Endoglucanase H (Gene Name=celH);
P59540

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