Structure of PDB 7xke Chain R

Receptor sequence
>7xkeR (length=253) Species: 10090 (Mus musculus) [Search protein sequence]
MALTFITYIGCGLSSIFLSVTLVTYIAFEKIRRDYPSKILIQLCAALLLL
NLIFLLDSWIALYNTRGFCIAVAVFLHYFLLVSFTWMGLEAFHMYLALVK
VFNTYIRKYILKFCIVGWGIPAVVVSIVLTISPDNYGIPNGTPDDFCWIN
SNVVFYITVVGYFCVIFLLNVSMFIVVLVQLCRIKKKKQLGIQDLRSIAG
LTFLLGITWGFAFFAWGVNVTFMYLFAIFNTLQGFFIFIFYCAAKENVRK
QWR
3D structure
PDB7xke Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
ChainR
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AND R L620 P762 N763 T765 M853 F856 L3 P139 N140 T142 M223 F226
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7xke, PDBe:7xke, PDBj:7xke
PDBsum7xke
PubMed35982227
UniProtQ8CJ12|AGRG2_MOUSE Adhesion G-protein coupled receptor G2 (Gene Name=Adgrg2)

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